Activation of pyruvate dehydrogenase in the perfused rat liver by vasopressin.
نویسندگان
چکیده
The proportion of pyruvate dehydrogenase in its active form is doubled in rat liver within 5 min of addition of vasopressin to the perfusing medium.
منابع مشابه
Hormonal control of pyruvate dehydrogenase activity in rat liver.
A detailed study of the control of liver pyruvate dehydrogenase activity by various hormones was carried out with perfused liver and isolated hepatocytes. Vasopressin produced a significant increase in the enzyme activity in fed rats, and the time course and sensitivity of the response was similar to that of glycogen phosphorylase a. The enzyme from starved animals was resistant to hormonal act...
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Mitochondria were prepared by a method including a Percoll purification step after the rapid homogenization of livers of fed rats which had been perfused either under unstimulated conditions or in the presence of vasopressin and/or glucagon. The two hormones separately or together increased the total calcium content of the mitochondria. This enhancement was accompanied by parallel increases in ...
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عنوان ژورنال:
- The Biochemical journal
دوره 176 2 شماره
صفحات -
تاریخ انتشار 1978